• About Us
  • Advertise
  • Contact Us
  • DMCA
  • Follow on Google News
Saturday, May 17, 2025
  • Login
News Mirror
  • Home
  • India
    • National
    • State News
  • World
  • Business
  • Education
  • Entertainment
  • Lifestyle
    • Health & Fitness
    • Fashion & Beauty
    • Travel
    • Food
    • Photography
  • Finance/Money
  • Tech
    • App News
    • Gadgets
  • Auto
  • Others
    • Sports
    • Agriculture
    • Science
    • Astrology
    • Press Release
    • Religion
    • Social Work
No Result
View All Result
  • Home
  • India
    • National
    • State News
  • World
  • Business
  • Education
  • Entertainment
  • Lifestyle
    • Health & Fitness
    • Fashion & Beauty
    • Travel
    • Food
    • Photography
  • Finance/Money
  • Tech
    • App News
    • Gadgets
  • Auto
  • Others
    • Sports
    • Agriculture
    • Science
    • Astrology
    • Press Release
    • Religion
    • Social Work
No Result
View All Result
News Mirror
No Result
View All Result
Home Science

Novel technique may help in early detection of Cancer, Alzheimer’s, and Parkinson’s

News Mirror by News Mirror
February 24, 2021
in Science, Tech
Share on FacebookShare on Twitter

New Delhi: Scientists from Raman Research Institute (RRI) have developed a new technique to measure DNA modifications that can have applications in the early diagnosis of multiple diseases like Cancer, Alzheimer’s, and Parkinson’s diseases.

DNA conformation, in particular, it’s supercoiling, plays an important structural and functional role in gene accessibility as well as in DNA condensation. Alteration in DNA affects their expression and functions. DNA controls cell survival through the genetic code as well as via modifications to its structure. The scientific community was looking for a technique with very high resolution to measure such modifications of DNA structures and observe and understand the molecular mechanisms associated with it to track rare diseases.

RelatedPosts

Kingston Celebrates Holi with Special Offer on External SSDs

Upgrade Your Setup this Republic Day with Kingston’s Exclusive Offer!

The novel nanopore-based platform developed by the scientists can directly measure such modifications or branched DNA properties with the single-molecule resolution even with extremely low amounts of sample. The platform and associated analysis techniques developed by the team can quantitatively assess the distribution of supercoiled branches on DNA plasmids (DNA molecule outside the chromosome).

“Further optimization of the technique can help in the development of portable nano-bio sensors for detection and quantification of protein aggregates and cell-free DNA or nucleosomes. This may help in the early diagnosis of many diseases like Cancer, Alzheimer’s, and Parkinson’s diseases” said Prof GautamVivekSoni, the lead researcher. Currently, researchers at RRI are also exploring applications of this method for virus detection.

The measurement principle of the novel platform is analogous to the Archimedes principle. Individual analyte molecules are driven through a nanopore under an applied voltage, which, during translocation, results in a tiny electrical blip. Charges excluded by the analyte (supercoiled DNA) in the  nanopore are directly proportional to the volume of the particle and are directly measured as the current change. This method utilizes extremely low amounts of sample and can measure DNA structural changes ranging to a few nanometers resolution in the axis perpendicular to the translocation and few tens of nanometers along the translocation axis.

The research team comprise  Dr Sumanth Kumar Maheshwaram, Dr Koushik Sreenivasaa and Prof Gautam Vivek Soni. The research findings have been recently published in the journal ‘Nanoscale’. (India Science Wire)

Tags: DNA Modificationnanoporenew techniqueRRI
Previous Post

‘Crowd and Mask’ Monitoring System to prevent COVID-19

Next Post

Union Minister Dr Jitendra Singh lays the Foundation Stone of new Students’ Hostels in the premises of the famous Cotton University

Related Posts

Kingston Celebrates Holi with Special Offer on External SSDs
Tech

Kingston Celebrates Holi with Special Offer on External SSDs

March 17, 2025
Upgrade Your Setup this Republic Day with Kingston’s Exclusive Offer!
Tech

Upgrade Your Setup this Republic Day with Kingston’s Exclusive Offer!

January 21, 2025
Kingston Technology Remains Top DRAM Module Supplier for 2023
Tech

Kingston Technology Remains Top DRAM Module Supplier for 2023

December 8, 2024
Kingston Technology to Release CUDIMM Modules for Intel 800-Series Chipset
Tech

Kingston Technology to Release CUDIMM Modules for Intel 800-Series Chipset

November 7, 2024
Celebrate Diwali with Kingston: The Ultimate Blend of Innovation and Festive Cheer
Tech

Celebrate Diwali with Kingston: The Ultimate Blend of Innovation and Festive Cheer

November 4, 2024
Kingston’s Best Gifting Options to Strengthen Sibling Bonds This Bhai Dooj
Tech

Kingston’s Best Gifting Options to Strengthen Sibling Bonds This Bhai Dooj

November 4, 2024
Next Post

Union Minister Dr Jitendra Singh lays the Foundation Stone of new Students' Hostels in the premises of the famous Cotton University

India hosts First Meeting of BRICS Finance and Central Bank Deputies

Leave a Reply Cancel reply

Your email address will not be published. Required fields are marked *

Recommended.

Anujjindal.in Platform Introduces Micro E-learning Program for Competitive Exams

April 24, 2021
Mr. Avinash Singh-The multifaceted Personality and the man behind Yes Academy your earning system

Mr. Avinash Singh-The multifaceted Personality and the man behind Yes Academy, your earning system

June 3, 2022

Trending.

Meet Dr. Santhi Saravanan: An Accomplished Artist, Financial Advisor, and Inspirational Speaker

Meet Dr. Santhi Saravanan: An Accomplished Artist, Financial Advisor, and Inspirational Speaker

March 21, 2023
Rice Over Bread: How Lenexis Foodworks Captured India’s Chinese Food Market

Rice Over Bread: How Lenexis Foodworks Captured India’s Chinese Food Market

May 14, 2025
Feelaxo: The Platform That’s Transforming How India Books Salon and Spa Services

Feelaxo: The Platform That’s Transforming How India Books Salon and Spa Services

April 22, 2025
Ice Cream Works Launches Exciting New Line of Popsicles and Ice Cream Bars — All at Just ₹99

Ice Cream Works Launches Exciting New Line of Popsicles and Ice Cream Bars — All at Just ₹99

May 1, 2025
The User-friendly Interface of FairPlay Makes Betting Convenient for both Newcomers and Seasoned Players

The User-friendly Interface of FairPlay Makes Betting Convenient for both Newcomers and Seasoned Players

May 29, 2023
News Mirror

© 2022 News Mirror

  • About Us
  • Advertise
  • Contact Us
  • DMCA
  • Follow on Google News

Follow Us

No Result
View All Result
  • About Us
  • Advertise
  • Contact Us
  • DMCA
  • Home
  • Privacy Policy

© 2022 News Mirror

Welcome Back!

Login to your account below

Forgotten Password?

Retrieve your password

Please enter your username or email address to reset your password.

Log In